Immune training: Previous vaccines against other viruses might reduce severity of Covid-19 symptoms

One fascinating feature of the pandemic is the difference in the severity of the disease among infected people.
There is early research that indicates that if a person received vaccines against any virus before the pandemic, their immune systems might be primed to respond faster to a Covid-19 infection.
Dr. Andrew Bradley from the Mayo clinic said,
“When we looked in the setting of Covid disease, we found that people who had prior vaccinations with a variety of vaccines, for pneumococcus, influenza, hepatitis and others , appeared to have a lower risk of getting Covid disease.”
This concept is called “immune training,” and doctors have noticed it with other diseases. For example, people who get vaccinated for tuberculosis have a reduced chance of getting malaria. TB is caused by a bacteria and malaria is caused by a parasite. The organisms are unrelated.
There is no evidence that this will happen with Covid-19, but we are still very early in learning about Covid-19 and its response to immune training. Scientists want to consider all concepts from vaccine science and infectious disease treatment and prevention.
A bigger initial “viral load” increases severity of disease
When you are initially infected with a virus, the number of virus particles is not enough to cause symptoms. The virus particles have to enter cells, take over the cell replication mechanisms, reproduce themselves, kill the cells, move on to infect other cells.
This process gets repeated many times before there is enough cell damage for you to notice it. Once there is some critical mass of virus particles, it will be causing enough cell damage for you to feel bad and conclude that you are sick.
It also takes time for your immune system to figure out how to make antibodies and T cells that will remove the virus from your body and let your body heal. If the immune process starts in someone who has very few virus particles, it will be closer to completion by the time the person has enough virus particles to cause symptoms. He is more likely to have enough early immunity working to make his symptoms less severe, and his illness end faster, than someone who initially inhaled a huge number of virus particles.
This is where masks come in. If a very sick person coughs in your face, some big droplets containing a huge number of virus particles might enter your mouth, nose, or eyes. But if you are wearing a mask, those big particles won’t make it in to infect you. Tiny droplets might, but they will have far few virus particles. Theoretically, if you get sick, you have a better chance of having milder symptoms and getting better faster.
Social distancing works

Dr. Mark Siedner and others at Massachusetts General Hospital, the University of Pennsylvania, and the University of London are reporting in a soon to be released paper that social distancing has been effective in slowing the spread of Covid-19 in the US. The researchers looked at a 3 week period in March when most states mandated social distancing.
They concluded that this reduced the number of new cases by 600,000. If the death rate was 1%, this would have saved 3,000 lives during those 3 weeks. One has to wonder how many lives would have been saved if this was mandated at the national level, as it was in the majority of developed countries, all of which have had far fewer deaths per capita than the US.
Herd immunity from recovering or from vaccination
I have written several times that the average Covid victim infects about 1.5 to 2 more people in the US. I have said how herd immunity requires about 70% of Americans to be immune, either after recovering from Covid or from vaccination.
We will have far fewer deaths if it comes mostly from people getting vaccinated. With only currently about half the country wanting to get vaccinated, a lot of the herd immunity will come from infected Americans.
But suppose the vaccine is not as effective as we hope. Or that it takes a year to get 50% of the country vaccinated. Then we could easily see a third of the country catch Covid.
The problem with that is that the death rate is at least 0.5 to 1%. One percent of 120 million infected people will result in over a million dead Americans. I have written repeatedly that by the time the pandemic ends, there will be between 500,000 and 1 million dead Americans. Also, if we handled this as well as the average developed country, probably 80% of those lives would have been saved. But it is what it is.
How many vulnerable Americans?
Many people overseas are experiencing schadenfreude over fat, rich, selfish, arrogant Americans getting their comeuppance. As I explained last week, obesity only accounts for a small part of our greatly increased number of deaths. The lack of national political leadership is by far our greatest problem.

Obesity is important, but there are many other factors as well that increase a person’s risk of getting very ill or dying from Covid. Simply being over age 60 is enough. All told, 30% of Americans are particularly vulnerable to becoming very sick if they come down with Covid.
Thirty percent means that all of us know many people who have a high risk of a serious form of Covid. If the pandemic has not touched your circle yet, it will.
How much more risk do Americans have compared to other developed countries?
Yes, the US has 22% of the world’s deaths with only 4% of the worlds’s population. But how does the US compare to other developed countries?
We chose to not create a national plan, although our politicians are claiming they are doing more than any other country. Sweden is an interesting comparison. Instead of their politicians doing nothing and claiming to be doing a lot, their politicians are doing nothing and claiming to be doing nothing. They decided to let the disease run its course and wait for herd immunity to develop on its own.
When you adjust for the size of the population, an American has the same risk as a Swede of dying from Covid. This makes sense because neither they nor we are doing anything at the national level to stop citizens from dying.
What about other developed countries? The average American is 2.1 times more likely to die than a Canadian and 4.5 times more likely than a German. Our risk is 35 times that of an Australian, 85 times greater than a South Korean, and 112 times greater than a New Zealander. All of those countries had leaders who created plans and led their citizens to participate in the fight against the virus.
I’m not opposed to leaders choosing to not have a plan, like Sweden, if a strong majority of the population agrees. The problem with the US is that most Americans expect our leaders to lead when there is a crisis. Remember JFK and the Cuban missile crisis or George W. Bush with his bullhorn after 911? If a leader turns around and only sees a handful of people following him, is he really a leader?
As you know, I believe we should have had a plan because the number of preventable deaths is shocking. There is no acceptable excuse. We don’t have to be South Korea. If we simply did what Germany did, more than 100,000 Americans would still be alive today.
Hospitals now have many more young Covid patients
Watching ignorant, foolish political leaders on the state and national level over the past 2 months essentially take credit for winning the war against the coronavirus was kabuki theater. I talked about how absurd this was in June and July. You can say that the pandemic is ending and that we are bending the curve, but that does not make it true. The virus is not going away, and to think otherwise is anti-science lunacy.
These arrogant, selfish anti-science fools encouraged people to resume their normal lives and the result was predictable. Also, telling young people that Covid is really a disease of the elderly and just a minor illness for people under 50 is nonsense.

Many 30 year old people are fat and in terrible shape. Their risk of getting a serious case of Covid is as high as that for a healthy 60 year old. Thirty years of age means nothing if you are fat and out of shape, giving your body the health of a 60 year old. About 10% of Millennials have high blood pressure, substance abuse, or high cholesterol, and 19% have diabetes. There are now more people hospitalized in the US from 18 to 49 years old than between 60 and 64 years old. Tens of thousands of people died over the past 2 months because many of these people trusted their leaders instead of common sense and science.
Coronavirus found on food
Well, it was only a matter of time. With tens of millions of infected people around the world, many food handlers would be infected. And many companies that process the food wouldn’t care.
Since June, there have been several reports of coronavirus on food and on food packaging in China. Health officials in Shenzhen, in their routine screening of imported meats, reported finding coronavirus on frozen chicken wings imported from Brazil. Health officials in Wuhu found it on the packaging of imported frozen shrimp from Ecuador.
There have been reports from other Chinese cities as well. The Chinese officials said that no one who may have come in contact with the contaminated packaging got sick.
I discussed fomite transmission a couple months ago. A fomite is any surface that can transmit the virus. I said that no one knows for certain, but fomite transmission, like from door knobs, sinks, or hand rails, probably only accounts for about 1% of Covid infects. The other 99% comes directly from someone’s mouth to your mouth, nose, or eyes, or indirectly via your hands.
Can you get Covid from eating?
I am unaware of any report of someone catching Covid from food. It is certainly possible, but cooking kills the virus.
If the virus is on the packaging and you touch it and then put your hand in your mouth, that could do it. However, that is extremely unlikely. Also, the viral load would be very small. If it were to happen, the person would probably get less sick than from someone coughing on them.
I heard more than one expert say that your stomach acid would kill the virus and therefore you would not get sick. That does not make sense. The virus-contaminated food would still have to pass through your mouth and esophagus before reaching your stomach. That would expose you to an infection.
But, again, there has not yet been a report of this. However, it is important to remember the math. With tens or hundreds of millions of infected people, even a 1 in a million thing will happen. There will eventually be a report of someone getting Covid from food.
Bill Gates expects pandemic over by end of 2021

Bill Gates is one of the richest people in the world and one of the world’s most respected infectious disease experts.
In a 2015 Ted Talk, he predicted that a worldwide virus pandemic was inevitable and it would cost $2 trillion. This one will probably cost $10 trillion.
Wired.com interviewed Bill Gates last week and here are some of his notable quotes:
“I’m surprised at the US situation because the smartest people on epidemiology in the world, by a lot, are at the CDC… You would expect the CDC to be the most visible, not the White House or even Anthony Fauci. But they haven’t been the face of the epidemic…They have basically been muzzled since the beginning. We called the CDC, but they told us we had to talk to the White House a bunch of times. Now they say, ‘Look, we’re doing a great job on testing, we don’t want to talk to you.’ Even the simplest things, which would greatly improve this system, they feel would be admitting there is some imperfection and so they are not interested.“
“The White House didn’t allow the CDC to do its job after March… So the variance between the US and other countries … are [sic] not the CDC’s fault. They said not to open back up. They said that leadership has to be a model of face mask usage. I think they have done a good job since April, but we haven’t had the benefit of it … for the rich world, we should largely be able to end this thing by the end of 2021, and for the world at large by the end of 2022.“
“Before the epidemic came, we saw huge potential in the RNA vaccines—Moderna, Pfizer/BioNTech, and Curevac. Right now, because of the way you manufacture them, and the difficulty of scaling up, they are more likely—if they are helpful—to help in the rich countries. They won’t be the low-cost, scalable solution for the world at large. There you’d look more at AstraZeneca or Johnson & Johnson.”
“This disease, from both the animal data and the phase 1 data, seems to be very vaccine preventable. There are questions still. It will take us awhile to figure out the duration [of protection], and the efficacy in elderly, although we think that’s going to be quite good.“
“The FDA, to their credit, at least so far, is sticking to requiring proof of efficacy. So far they have behaved very professionally despite the political pressure. There may be pressure, but people are saying no, make sure that that’s not allowed. The irony is that this is a president who is a vaccine skeptic. Every meeting I have with him he is like, ‘Hey, I don’t know about vaccines, and you have to meet with this guy Robert Kennedy Jr. who hates vaccines and spreads crazy stuff about them.'”
Q: Wasn’t Kennedy Jr. talking about you using vaccines to implant chips into people?
“Yeah, you’re right. He, Roger Stone, Laura Ingraham. They do it in this kind of way: ‘I’ve heard lots of people say X, Y, Z.’ That’s kind of Trumpish plausible deniability. Anyway, there was a meeting where Francis Collins, Tony Fauci, and I had to [attend], and they had no data about anything. When we would say, ‘But wait a minute, that’s not real data,’ they’d say, ‘Look, Trump told you you have to sit and listen, so just shut up and listen anyway.’ So it’s a bit ironic that the president is now trying to have some benefit from a vaccine.”
Q: But people aren’t getting their tests back quickly enough.
“Well, that’s just stupidity. The majority of all US tests are completely garbage, wasted … When we tell them [the government] to change it they say, ‘As far as we can tell, we’re just doing a great job, it’s amazing!’ Here we are, this is August. We are the only country in the world where we waste the most money on tests. Fix the reimbursement. Set up the CDC website. But I have been on that kick, and people are tired of listening to me.”
Q: As someone who has built your life on science and logic, I’m curious what you think when you see so many people signing onto this anti-science view of the world.
Well, strangely, I’m involved in almost everything that anti-science is fighting. I’m involved with climate change, GMOs, and vaccines. The irony is that it’s digital social media that allows this kind of titillating, over-simplistic explanation of, ‘OK, there’s just an evil person, and that explains all of this.’ And when you have [posts] encrypted, there is no way to know what it is. I personally believe government should not allow those types of lies or fraud or child pornography [to be hidden with encryption like WhatsApp or Facebook Messenger].
Dr. Brooks’s earlier special reports on the Covid-19 pandemic:
- 35 overrated Covid-19 vaccines, anti-vax, obesity, and drug business profits
- Covid-19: Heart disease, Russian vaccine, and the end of the hydroxychloroquine hoax
- Many Covid vaccines and treatments, and less flu
- The coronavirus pandemic: Biggest worldwide event of our lifetimes
- Covid-19 pandemic vaccine and its euphoric market impact
Oh well. Sorry to say but have had to close comments on this post. Al is not at all happy with the personal attacks which detract from the topic by a large margin.
Could I ask those who want to comment to simply share on their favorite social media channel. Better to see social shares (only 1 here to date) rather than multiple comments upsetting members with off-topic rants and attacks.
So much for free speech, eh? Homo sapiens needs to do much, much better if we are to survive as a species. 😉
Apparently SARS-CoV-2 can not only afflict people physically with infection but can afflict people mentally without infection.
HenryFord.com: Hydro Treatment Study
DETROIT – Treatment with hydroxychloroquine cut the death rate significantly in sick patients hospitalized with COVID-19 – and without heart-related side-effects, according to a new study published by Henry Ford Health System.
In a large-scale retrospective analysis of 2,541 patients hospitalized between March 10 and May 2, 2020 across the system’s six hospitals, the study found 13% of those treated with hydroxychloroquine alone died compared to 26.4% not treated with hydroxychloroquine. None of the patients had documented serious heart abnormalities; however, patients were monitored for a heart condition routinely pointed to as a reason to avoid the drug as a treatment for COVID-19.
The study was published today in the International Journal of Infectious Diseases, the peer-reviewed, open-access online publication of the International Society of Infectious Diseases (ISID.org).
“The findings have been highly analyzed and peer-reviewed,” said Dr. Marcus Zervos, division head of Infectious Disease for Henry Ford Health System, who co-authored the study with Henry Ford epidemiologist Samia Arshad. “We attribute our findings that differ from other studies to early treatment, and part of a combination of interventions that were done in supportive care of patients, including careful cardiac monitoring. Our dosing also differed from other studies not showing a benefit of the drug. And other studies are either not peer reviewed, have limited numbers of patients, different patient populations or other differences from our patients.”
End of Article Excerpts
Related Facts:
About Henry Ford Health System
Henry Ford Health System is committed to improving the health and well-being of our diverse Michigan community
Founded in 1915 by auto pioneer Henry Ford and now one of the nation’s leading health care providers, Henry Ford Health System is a not-for-profit corporation managed by Chief Executive Officer Wright L. Lassiter, III and governed by a 17-member Board of Trustees, with volunteer-led advisory and affiliate boards providing additional leadership.
It is comprised of hospitals, medical centers and one of the nation’s largest group practices, the Henry Ford Medical Group, which includes more than 1,200 physicians practicing in over 40 specialties. The System’s flagship, Henry Ford Hospital in Detroit, is a Level 1 Trauma Center recognized for clinical excellence in cardiology, cardiovascular surgery, neurology and neurosurgery, orthopedics, sports medicine, multi-organ transplants and cancer treatment.
With more than 30,000 employees, Henry Ford Health System is the fifth-largest employer in metro Detroit, and among the most diverse.
Marcus J Zervos, MD
Board Certification and Education
Board Certifications
American Board of Internal Medicine – Infectious Disease
American Board of Internal Medicine – Internal Medicine
Education
Wayne State University, MI, 1979
Residencies & Internships
Wayne State University, Medicine, MI, 1983
Wayne State University, Internal Medicine, MI, 1980
Fellowships
University of Michigan, Infectious Disease, MI, 1986
Additional:
MN Governor Quietly Reverses Course on Hydroxychloroquine
This past week Minnesota became the second state to reject regulations that effectively ban the controversial drug hydroxychloroquine for use by COVID-19 patients.
The decision, which comes two weeks after the Ohio Board of Pharmacy reversed an effective ban of its own, was rightfully praised by local health care advocates. “We are pleased that Governor [Tim] Walz lifted his March 27 Executive Order 20-23 restrictions on chloroquine and hydroxychloroquine,”
The reversal by Walz, a first-term Democrat, clears the way for doctors to prescribe hydroxychloroquine.
Though his critics are likely loath to admit it, there’s reason to believe the president may have been on to something. In recent weeks a chorus of voices in the medical community has emerged to challenge the view that hydroxychloroquine is ineffective as a COVID treatment.
My Thoughts:
The doctor that did the study at Henry Ford Health Systems is board certified, and unlike Dr. “Saint” Fauci, this guy actually sees and treats patients. The study was also peer-reviewed.
If “King” Trump had came out and spoke negatively about HCQ back in March, the Dems would have been accusing him of murder and vilified him.
Trump could eradicate cancer and the Dems would call him a racist because he “ignored” Sickle Cell Anemia.
Reality is, any evidence showing HCQ helps treat the China Virus will be dismissed by all the Trump haters. 🙁
Reputable journal, good med center. I am interested to see how other infectious disease experts analyse the report.
I think one problem with how experts can respond, is that it can be “unsafe” for them to agree that HCQ is beneficial because they will be accused of supporting President Trump.
Even though I support “The King”, I know he makes it real easy for people to hate him. He’s thin-skinned, narcissistic, and doesn’t act presidential at times. I agree most things he has done, but I do wish he would think before he tweets at times. It’s a different time we live in though. I sometimes wonder if Social Media is “The Antichrist”.
Thanks for doing these posts, Al. I know your heart is in the right place. I know you are frustrated with how the country has responded to the virus. You’ve said before that every day you just want to do good. But doing good, hasn’t been the focus of politicians when it comes to this crisis. Personally, I think Trump was ill-prepared to handle the virus, but I also think the Democrats saw it from the start as something they could use politically against Trump and gain more power.
Thanks, Al, for reading what I posted earlier, and in advance for reading this post. Take care!!
If we all agree that Sweden and USA took the same approach – no plan (even though USA claims to have a plan and Sweden decided to not have a plan) how do you explain the fact that Sweden has 8340 cases per one million and USA has 16805 cases per one million. And there are no new cases in Sweden while USA is experiencing a second wave.
I think “new cases” encompasses too many variables in its calculation, and therefore there is going to be a lot of variability. I don’t think that it is a reliable measure for comparison.
Deaths are easier to compare, but even that is not always certain. For example, many countries lie and others do not count a death unless the person was completely healthy with no other medical problems before getting Covid.
Russia is an example. They have lots of cases but a very low death rate. Also, I suspect there is no strong political incentive for them to be honest with any of their data.
We all don’t agree with your statement, and your numbers are conveniently wrong; Sweden has 84.3k confirmed cases and 5.8k deaths (as of 8/17) with a case-fatality ratio of 6.9% and 57 death per 100k population. The US has case-fatality of 3.1% and 52 death per 100k population. No new cases in Sweden? check your source.
Please stick to trading. We don’t all agree with your views, and they shouldn’t be voiced here. They feel very condesending, and in my life experience typical of those from the medical world who think only science and their views are right. This website is about trading, and should not be an area where you wish to force your idiological views about what you think is what we should think on us. You ought to start a separate blog site for these topics tbh. It’s obvious you’re posting here because you have an audience you can voice your strong feelings. Please stick to trading.
You are here to learn from Al Brooks. Please show some respect, to man that is gracious enough to teach others; when he does not need to. Al Brooks, predicted the pandemic before it happen.
Attempting to censor not just the principle of free speech but the medium from which the author chooses to communicate his analysis…the medium which he owns. Mind blowing!
The analysis on covid impacts is related to trading because the research provided helps differentiate what sectors to speculate in long and short positions.
There are voluminous other blogs and online channels that will tell you what you want to hear. Let me know if you need recommendations! I know exactly what you’re looking for.
If you can’t read an opinion without it hurting your feelings, go away and find opinions that don’t offend you.
I like what Al is writing, it’s his website anyway, who are you to judge here.
I fail to comprehend what compels your mouse to wander to Al’s Covid articles all by itself.
Funny. Tell Al that he shouldn’t do what you don’t like on his website. He can do whatever he likes. Likewise, you can set up your own website and do what you like there. Read carefully what Al wrote about virus. You may learn a few things that will save your life
“They feel very condescending, and in my life experience typical of those from the medical world who think only science and their views are right.”
(I had to correct some spelling so not a direct quote, sorry. I do think it is important spelling condescending right though when this is the point of the post.)
YES! WTF is up with all this science stuff. Like things need to be proved or something!! Like Evolution theory actually in some part of the world take precedence over religion, just because science can prove their theories and religion “only” have this book approved by a group of religious men in Nikea around year 300.
And who really cares about scientific methods and proof. Homoeopathy (spelling) actually had fewer deaths in their hospital in London in the 19th century (when medicine didn’t care much about science and main treatment were “bloodletting”. Homoeopathic medication was as now, still just water so they “did no harm at least”)
I am just unsure what you do on a website that is built on probability and statistics, but in real life, you like the science which maybe 1-10% of scientist supports and completely disregard the higher probability (that maybe the 90-99% is right, and is not banned on Youtube, accepted and use rules regarding experiments, so the experiments result can be reproduced etc etc…)
re. Immune training…. apparently the 1960s live polio vaccine looks particularly helpful for this… research in progress.
Please look into senolytics to remedy Immune Senescence.